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Center for Chronic Disease Outcomes Research


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Minneapolis Evidence-based Synthesis Program

The Minneapolis VA Evidence Synthesis Center located in CCDOR is led by Timothy Wilt, MD, MPH, and receives funding through the VA HSRD program to conduct systematic reviews of the effectiveness and comparative effectiveness and harms of high impact topics.


  • Our ESP report on Screening Pelvic Exams provided the evidence base for the American College of Physicians Clinical Practice Guideline on Pelvic Exams. It also has been used by the VA Office of Women’s Health to inform Healthcare practice and policy for Women Veterans. Assessment of its impact in FY15 in the year following its release showed that this guideline has received the most media stories (1,533) and total audience review (188,792,658) and the 2nd most number of web hits (83,000) of any ACP evidence report and clinical guideline.
  • Effectiveness and Harms of Pharmacist-Led Chronic Disease Management the Benefits and Harms for the Mediterranean Diet Compared to Other Dietary Interventions were published in Annals of Internal Medicine.
  • The Pharmacist Led Care report had considerable positive media coverage and was presented as a VA Cyberseminar.


For more information about the National VA Evidence-based Synthesis Program, click below.