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Center for Chronic Disease Outcomes Research


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AHRQ and VA Evidence Synthesis Programs (Dr. Tim Wilt, Director)
Funding through both the Agency for Healthcare Research and Quality (AHRQ) and the VA HSR&D program have provided support to conduct systematic reviews of the effectiveness and comparative effectiveness and harms of several high impact topics including: Screening Pelvic Examinations, Fecal Microbiota Transplation for Clostridium Difficile Infection, Shared Decision Making on Cancer Screening, and Cultural Competence Interventions to Reduce Health Disparities in Priority Populations. These systematic reviews lead to peer-reviewed publications, clinical practice guidelines, consensus conference recommendations and/or practice change.

Other VA/ORD Operations Partnership
Dr. Partin was asked to serve as an Implementation Science representative on the Veterans Health Affairs National Colorectal Cancer Screening and Surveillance Reminder System Workgroup. Initiated by the Gastroenterology Field Advisory Committee, this interdisciplinary workgroup is developing a new, nationally standardized clinical reminder for colorectal cancer screening and surveillance for the VHA.

Responding to requests from the Office of Heath Equity
Dr. Spoont and her team analyzed data from a longitudinal cohort study of Veterans being treated for PTSD and found disparities for African American and Latino Veterans in pharmacotherapy retention not due to differences in treatment need, access or treatment availability, and only partially due to beliefs about medication among Latino Veterans. Recommendations for addressing PTSD treatment disparities were requested by the Director of the Office of Health Equity (OHE), Uchenna Uchendu, MD, and were delivered: Spoont MR, Schnurr P, Hoff R, O' Brien R, Ruzek J, Burgess DJ, Hamblen J, Norman S, Ruggerio K, Kehle-Forbes SM. Internal Report on Recommendations to Address Racial and Ethnic Disparities in VHA Treatment of PTSD. 2015 Jan 30. Also at the request of the OHE director, results were disseminated in two Cyberseminars: PTSD Consultation Program Lecture Series 2015, (National Center for PTSD Cyberseminar), April 15, 2015, and Spoont MR, Nelson DB,
Murdoch M, Sayer NA, Rector TS, Westermeyer J. Racial and Ethnic Disparities in PTSD Treatment: Findings from a National Cohort Study. [HSR&D Cyberseminar]. 2015 Jun 24.

National (non-VA)
American College of Physicians Clinical Practice Guideline Committee and the VA
Preventive Medicine Advisory Committee

Dr. Wilt serves on several clinical guideline groups that make evidence-based recommendations on disease detection, prevention, treatment and health promotion to improve the lives of Americans. Recommendations issued in the past year include: screening for and management of obstructive sleep apnea, prevention of recurrent nephrolithiasis, screening for and monitoring of chronic kidney disease, prevention of pressure sores in hospitalized patients, screening for thyroid dysfunction, and pelvic examinations. These recommendations are likely to have major clinical impact on our Veterans.

American Medical Association (AMA) Task Force to Reduce Opioid Abuse
Dr. Krebs serves as the American College of Physicians (ACP) clinical representative to
the American Medical Association (AMA) Task Force to Reduce Opioid Abuse.

Prior Impacts

News and Media Coverage:
Featured Projects:
  • Diana Burgess, PhD and colleagues are testing the effectiveness of a multi-component intervention involving proactive outreach, a pedometer-based walking program, action planning, motivational interviewing and the use of cognitive behavioral techniques among black and non-black Veterans with chronic musculoskeletal pain. More Information
  • Erin Krebs, PhD, MPH was awarded $12.5 million from the Patient-Centered Outcomes Research Institute (PCORI) to conduct a comparative effectiveness study to improve pain management and opioid safety in Veterans with chronic pain. More Information